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Bupropion was associated with the least amount of weight gain, close to none. Side effects such as insomnia, drowsiness, dry mouth, nausea, and increased sweating may more Prescription only. Selegiline (Emsam), a newer MAOI that you apply to your skin, which may lead to fewer side effects than MAOIs taken by mouth Weight gain is also less likely to occur with the following SSRIs when. The same can be said for side effects A large proportion of patients treated with paroxetine, mirtazapine, and other antidepressants, such as venlafaxine (EFFEXOR®, EFFEXOR XR®), gain a significant amount of weight. I have been reading forums and articles, and a lot of them said that Citalopram causes a lot of weight gain. Amitriptyline and nortriptyline are older drugs. Two others that also appeared to have less weight gain were amitriptyline and nortriptyline. Food and Drug Administration (FDA) announced the approval of a once-daily atypical antipsychotic drug, Lybalvi ( olanzapine and samidorphan), to treat adults with schizophrenia and adults. Though mirtazapine is not widely prescribed anymore, citalopram is. Other antidepressants that appear less likely to have weight gain as a side effect include: Cymbalta (duloxetine) Effexor (venlafaxine) Lexapro (escitalopram) Pristiq (desvenlafaxine) Trintellix (vortioxetine) An antidepressant that works well for one person may not be as effective for another. I am very active and I eat very well, but I am concerned that the Citalopram will cause me to gain a lot of weight.. Verywell / Andrea Hickey Nearly all antidepressants have the potential side effect of causing weight gain — 1 including Celexa (citalopram), a selective serotonin reuptake inhibitor (SSRI) similar to Prozac (fluoxetine) or Zoloft (sertraline) Hi all. I am a recently diagnosed Type 1 diabetic, and the insulin therapy already makes it tough to keep my weight stable. In a 2014 study of more than 22,000 patient records, amitriptyline, bupropion (Wellbutrin SR, Wellbutrin XL), and nortriptyline (Pamelor) caused less weight gain than citalopram over the course of. Because newer drugs tend to have fewer side effects, those two aren’t prescribed as frequently According to the study, people who took citalopram (brand name Celexa) or mirtazapine (Remeron) were more likely to gain weight.

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